Recently published review   articles: Inherited Causes of Sudden Death. (read more)

 
 
Arrhythmogenic right ventricular dysplasia (ARVD), also known as arrhythmogenic right ventricular cardiomyopathy (ARVC), is an inherited cause for sudden cardiac arrest. In ARVD, there is progressive replacement of the normal tissue of the right ventricle by fat and fibrous tissue (scar tissue). This may lead to abnormal electrical activity of the right ventricle and potentially dangerous arrhythmias. ARVD may be diagnosed by characteristic abnormalities of the electrocardiogram and by sophisticated imaging tests of the heart. (read more)
 
Brugada Syndrome (BS) is a genetic cause of sudden cardiac arrest. Lethal arrhythmia (irregularity of the heart rhythm) may arise from the ventricles, the lower chambers of the heart, which prevent the ventricles from contracting effectively. Without prompt defibrillation (electrical shock), death may ensue within a few minutes. Brugada syndrome may be diagnosed before such an event by characteristic abnormalities on the electrocardiogram. (read more)
 
Familial Dilated Cardiomyopathy causing heart failure is a progressive condition in which the heart's muscle becomes weakened after injury and gradually loses its ability to pump enough blood to supply the body's needs. Many people are unaware of the diagnosis because the symptoms are often mistaken for the subtle symptoms of advancing age. Heart failure usually does not develop overnight it is a progressive disease that starts slowly and gets worse over time. Though most cases of dilated cardiomyopathy occur in a sporadic pattern, dilated cardiomyopathy may be inherited and affect multiple family members. (read more)
 
Hypertrophic Cardiomyopathy (HCM) is a complex cardiac disease marked by thickening of the heart muscle. In HCM patients this thickening occurs for no apparent clinical cause like significant high blood pressure. The disease doesn't affect everyone the same way, with different degrees of muscular wall thickening and a variety of symptoms. Patients may have shortness of breath, exercise intolerance, chest pressure or pain, fainting, or no symptoms at all. In unusual cases HCM can cause sudden cardiac death. (read more)
 
Congenital Long QT Syndrome(LQTS) is a genetic disorder that can lead to abnormal electrical activity in the heart muscle known as arrhythmia. The many different mutations that lead to congenital LQTS are commonly called channelopathies. Channelopathies are disorders caused by mutations in genes that encode for protein channels.  These mutations lead to disrupted flow of sodium, potassium, and calcium ions in and out of the cardiac muscle cell. The ventricular arrhythmias caused by Long QT syndrome can result in loss of consciousness or sudden death in children and young adults. Identification of an abnormal electrocardiogram (EKG) can diagnosis patients with this condition: the EKG shows a prolonged QT interval and/or abnormal T wave shape. (read more)